[İş Radarı](https://jobradar.live/) / [Jobs](https://jobradar.live/ilanlar) / Associate Director / Director, Clinical Science Active On-site Bothell, Washington, United States Posted · 20.09.2026 Greenhouse (US) # Associate Director / Director, Clinical Science Immunome, Inc. Company Overview Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets. Position Overview Immunome is seeking a highly experienced and strategic Associate Director / Director, Clinical Science to provide scientific leadership for clinical development programs across our oncology portfolio. This role will be responsible for shaping clinical strategy, authoring and reviewing key clinical documents, and ensuring scientific rigor in the design, conduct, analysis, and interpretation of clinical studies.   The successful candidate will bring deep expertise in oncology drug development, strong cross-functional leadership in a matrix organization, and the communication skills required to translate complex clinical data into clear recommendations. This position offers a highly visible opportunity to influence clinical development plans and help advance Immunome’s innovative targeted therapies.   Responsibilities Strategic Leadership   Partner with Clinical Development leadership to define clinical strategy and contribute to integrated clinical development plans for assigned programs.  Provide scientific leadership for clinical study design (Phase 1–3), including endpoints, eligibility criteria, dose and regimen rationale, and biomarker strategy.   Serve as a key clinical development voice in program governance, enabling timely, data-driven decisions that balance patient safety, scientific value, and development timelines.   Program Oversight and Execution   Lead the scientific execution of clinical studies, collaborating with Clinical Operations, Data Management, Biostatistics, Clinical Pharmacology, Translational Medicine, and Safety to ensure high-quality conduct.  Support medical monitoring activities, including review of safety data, protocol deviations, and emerging risk/benefit considerations, in partnership with Medical Directors and Pharmacovigilance.   Review and interpret clinical data (safety, efficacy, PK/PD, biomarkers), generate insights, and communicate results to internal teams and external stakeholders.   Vendor and Partner Management   Provide clinical development oversight of CROs and vendors (e.g., central labs, imaging, biomarkers) to ensure alignment with protocol requirements and data quality expectations.  Collaborate with external investigators, steering committees, and key opinion leaders to support study execution, recruitment, and scientific communication.   Regulatory and Documentation Support   Author, review, and contribute to clinical protocols, amendments, investigator brochures, informed consent forms, statistical analysis plans (in partnership), clinical study reports, and regulatory submissions (IND/CTA, annual reports, briefing packages).  Contribute to responses to health authority questions and support regulatory interactions by providing clear clinical development rationale and data interpretation.   Ensure all clinical development activities comply with GCP, applicable regulations, and internal quality standards.   Leadership and Collaboration   Lead, mentor, and develop clinical scientists and/or contractors, fostering a culture of scientific excellence, accountability, and collaboration.  Drive alignment across cross-functional teams, proactively identifying risks, proposing mitigation plans, and ensuring clear communication of priorities and decisions.  Support scientific dissemination through abstracts, manuscripts, presentations, and investigator meeting materials.   Qualifications PhD, PharmD, MD, or equivalent advanced degree in a life science discipline with 5+ years of experience in clinical development (oncology preferred).  Demonstrated experience designing and executing oncology clinical trials, including protocol development, endpoint selection, and operational feasibility considerations.  Proven track record authoring and reviewing key clinical documents and contributing to regulatory submissions and/or health authority interactions.  Experience interpreting clinical and translational data (safety, efficacy, PK/PD, biomarkers) and presenting findings to diverse audiences.   Strong understanding of ICH/GCP and global clinical development regulations and guidance.   Experience leading in a matrix environment and managing external vendors/partners; prior people management experience is a plus.   Knowledge and Skills Deep knowledge of clinical trial design and execution across phases, with a strong scientific foundation in oncology and targeted therapeutics.  Expertise in writing, reviewing, and QC’ing clinical documents (protocols, ICFs, IBs, CSRs, briefing documents) with attention to detail and regulatory expectations.  Ability to synthesize complex datasets and translate findings into clear scientific narratives and actionable recommendations.   Strong cross-functional leadership and project management skills, with the ability to drive alignment and decision-making in a fast-paced environment.   Excellent verbal and written communication skills, including experience presenting to internal governance and external scientific audiences.  Collaborative, proactive working style with sound judgment, integrity, and a commitment to patient safety and data quality.   Demonstrated ability to manage priorities across multiple programs and meet aggressive timelines.   Experience mentoring and developing scientific staff, building strong internal and external networks.      Washington State Pay Range • Associate Director: $177,571 - $212,160 Washington State Pay Range • Director: $221,245 - $263,327 Washington State Pay Range$177,571—$263,327 USDE/E/O Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. E-Verify Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish). This job was verified from Greenhouse (US). Applications are completed on the original source. [Apply on the original listing ↗](https://jobradar.live/ilan/d7c47137-4f9f-4080-a8f9-cca4543987a3/git) ## Stop searching one by one for roles like this. Upload your resume or enter your target roles to see your first 3 matches for free. [Find jobs for me →](https://jobradar.live/uye/kayit) Your resume is never shared with employers; it is processed only for matching. Something wrong with this job?