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United States
Posted · 20.09.2026
Greenhouse (US)

# Director, Field Medical - Central

Maze Therapeutics

The Opportunity We’re&nbsp;looking for a Director of Field Medical to&nbsp;serve as the regional scientific lead during a pivotal stage of&nbsp;our&nbsp;growth. This senior, full-scope Medical Science Liaison role&nbsp;rests on two&nbsp;pillars: leading&nbsp;high-level scientific exchange and key opinion leader relationships across&nbsp;your&nbsp;region&nbsp;and serving&nbsp;as the field-facing scientific partner to Maze's clinical development programs.&nbsp;It’s&nbsp;a genuine scientific leadership position,&nbsp;not site support with a scientific veneer.&nbsp; With MZE829&nbsp;entering its&nbsp;pivotal program in 2027 and MZE782 advancing through Phase 2,&nbsp;your&nbsp;immediate priority is enabling the clinical programs, so trial and investigator support&nbsp;carries&nbsp;real weight from day one.&nbsp;Because Maze is genetics-first,&nbsp;you’ll&nbsp;need credibility across&nbsp;two distinct communities:&nbsp;nephrology (AMKD, FSGS, CKD) and metabolic disease (PKU).&nbsp;&nbsp;Initially,&nbsp;an&nbsp;individual contributor,&nbsp;you’ll&nbsp;build&nbsp;the&nbsp;region's scientific relationships and support trial execution, then&nbsp;help recruit, mentor, and eventually lead a regional&nbsp;MSL team as we grow&nbsp; The Impact You’ll Have Scientific Exchange &amp; KOL Engagement&nbsp; You’ll&nbsp;be&nbsp;a&nbsp;recognized scientific expert and the trusted face of Maze&nbsp;in your regions.&nbsp; Lead&nbsp;compliant, peer-to-peer scientific exchange with thought leaders, physicians, renal pathologists, and PKU specialists, and build a durable regional KOL&nbsp;map, including&nbsp;in a metabolic community where Maze&nbsp;isn’t&nbsp;yet known.&nbsp; Provide&nbsp;accurate&nbsp;scientific education on AMKD, FSGS, CKD, and PKU, including APOL1 biology and SLC6A19 substrate reduction,&nbsp;and respond to unsolicited medical&nbsp;inquires.&nbsp; Represent&nbsp;Maze at major congresses (ASN, NKF, and metabolic/PKU societies)&nbsp;and&nbsp;support advisory boards,&nbsp;scientific meetings, and&nbsp;patient advocacy&nbsp;partnerships.&nbsp;&nbsp; Clinical Development &amp; Investigator Partnerships&nbsp; The immediate&nbsp;priority.&nbsp;You’ll&nbsp;be&nbsp;the field-facing scientific partner accountable for site engagement and&nbsp;scientific barriers affecting&nbsp;enrollment across&nbsp;your&nbsp;region.&nbsp; Serve as the&nbsp;regional&nbsp;scientific partner&nbsp;to&nbsp;Maze's&nbsp;trials, including HORIZON and the MZE829,&nbsp;and MZE782, and the single point of contact for investigators and sites.&nbsp;&nbsp; Shape site&nbsp;selection&nbsp;through feasibility input,&nbsp;and support site identification, investigator meetings, and start-up.&nbsp; Own the field-side response to enrollment and retention barriers,&nbsp;driving&nbsp;compliant scientific solutions with Clinical Operations.&nbsp; Genetic Testing &amp; Patient Identification&nbsp; Support adoption of APOL1 genotyping&nbsp;and&nbsp;advance genotype-driven patient identification pathways, the mechanism by which eligible patients reach the trials.&nbsp; Address&nbsp;the trust and access barriers facing an AMKD population disproportionately of African ancestry,&nbsp;a concrete enrollment lever, not a peripheral consideration.&nbsp; Medical Insights &amp; Strategic Input&nbsp; Capture field insight (treatment patterns, unmet need, evidence gaps, competitive intelligence) on a consistent cadence, and&nbsp;translate&nbsp;it&nbsp;into recommendations that&nbsp;shape&nbsp;medical strategy, evidence generation, and launch readiness.&nbsp;&nbsp;Because Maze is small, these insights land directly with the people who set direction.&nbsp; Building the Field Medical Organization&nbsp; Carry your&nbsp;assigned territory personally&nbsp;as&nbsp;the senior regional scientific leader, and&nbsp;help recruit,&nbsp;mentor,&nbsp;and develop MSLs as&nbsp;we&nbsp;scale, growing into regional team leadership over the next 1–2 years.&nbsp; As a&nbsp;Director, we also expect&nbsp;you&nbsp;to&nbsp;demonstrate&nbsp;the following Leadership Competencies: &nbsp; Communication&nbsp;and Influence&nbsp; Builds communication channels across Maze for sharing information&nbsp; Influences Senior Management decisions through persuasive arguments&nbsp; Respectfully addresses differing opinions leading to support of decision&nbsp; Teamwork and&nbsp;Collaboration&nbsp; Champions partnerships and connections across Maze&nbsp; Proactively addresses issues that could result in breakdown of team relationships&nbsp; Spotlights team and individual contributions in public forums&nbsp; Execution and Results&nbsp; Addresses gaps and leverages strengths to get best results&nbsp; Maintains a steadying presence and clarifies priorities during change&nbsp; Anticipates and removes barriers that put functional/corporate goals at risk&nbsp; Develop Others and Self&nbsp; Removes barriers to staff development and empowers them to make their own decisions&nbsp; Stays current on industry trends and keeps direct-reports prepared and responsive&nbsp; What We’re Looking For What&nbsp;you’ll&nbsp;need&nbsp; An advanced scientific degree (PharmD, PhD, MD, DO, or equivalent).&nbsp; a minimum of 7 years of Medical Affairs, Field Medical, Clinical Development, or related biopharmaceutical experience.&nbsp; A demonstrated&nbsp;track record&nbsp;building&nbsp;KOL&nbsp;relationships and leading peer-to-peer scientific exchange. This is a core requirement, not a nice-to-have;&nbsp;if&nbsp;you’re&nbsp;strong on trial&nbsp;logistics&nbsp;but light on scientific engagement and KOL relationships, this role&nbsp;isn’t&nbsp;the right&nbsp;fit.&nbsp; Demonstrated accountability for site engagement and clinical trial enrollment, not solely data presentation at sites.&nbsp;&nbsp; Deep scientific fluency and the credibility to hold a peer-level conversation with an academic specialist.&nbsp; Willingness to travel&nbsp;approximately 60–70% within the assigned region.&nbsp; What would be great to have&nbsp; Nephrology depth with existing relationships in the kidney community, and genuine willingness to build metabolic and PKU fluency.&nbsp; Pre-commercial or first-launch biotechnology experience, built without an established field infrastructure.&nbsp; Experience with genotype-driven patient identification and diagnostic testing pathways.&nbsp; Experience mentoring MSLs or&nbsp;leading congress&nbsp;and&nbsp;or&nbsp;scientific-platform&nbsp;initiatives.&nbsp; &nbsp; About Maze Therapeutics Maze Therapeutics is a clinical-stage biopharmaceutical company harnessing human genetics to develop precision medicines for patients with kidney and metabolic diseases. Our clinical pipeline is anchored by two small molecule programs: MZE829, an APOL1 inhibitor for patients with APOL1‑mediated kidney disease, and MZE782, which targets genetic drivers of disease in phenylketonuria (PKU) and chronic kidney disease. We are also advancing a preclinical pipeline through our Compass platform, which links human genetic variants to the biological pathways that drive disease. Our People Maze is comprised of a team of passionate and creative professionals committed to discovering and delivering transformative medicines to patients suffering from both rare and common genetic diseases. We are fostering a culture that encourages vision, initiative and the development of talent. Our supportive work environment inspires creative thinking and freedom of expression, resulting in a stimulating atmosphere where people enjoy coming to work. While we have a passion for advanced science and pride ourselves on excellence in execution, ultimately, everything we do is about patients.&nbsp; Our Core Values Further Together – Our path is paved with challenges, but with resilience and a team-first mentality, we’ll achieve our mission.&nbsp; Impact Obsessed – We embrace the bold, take calculated risks, and learn from our mistakes to improve the lives of others. Stand True – Our integrity is foundational; it guides us no matter the obstacle. The expected annual salary range for employees located in the San Francisco Bay Area is $205,000 - $295,000. Additionally, this position is eligible for an annual performance bonus. Maze performs position-based compensation benchmarking to industry market data to ensure we pay competitive wages. Determination of starting salary will depend upon a variety of job-related factors, which may include professional experience, skills, and job location. The expected salary range for this role may be modified in the future. Maze offers a robust benefits package to our eligible employees including competitive medical, dental, and vision insurance, mental health offerings, equity incentive plan, 401(k) program with employer match and a generous holiday and PTO policy. &nbsp; #LI-Remote

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