[Job Radar](https://jobradar.live/) / [Jobs](https://jobradar.live/ilanlar) / Scientist II, Clinical Pharmacology & Pharmacometrics Active On-site Bothell, Washington, United States Posted · 24.09.2026 Greenhouse (US) # Scientist II, Clinical Pharmacology & Pharmacometrics Immunome, Inc. Company Overview Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets. Position Overview The Scientist II, Clinical Pharmacology and Pharmacometrics will bring extensive experience in oncology quantitative pharmacology, clinical pharmacology strategy, and oncology drug development.   Responsibilities Formulate and deliver CP&MS strategy for late-stage and early preclinical / clinical development assets.   Apply pharmacokinetic/pharmacodynamics (PK/PD), physiologic based PK (PBPK) and pharmacometric modeling & simulation (M&S) approaches to characterize drug absorption and disposition and assess the dynamics of drug effect to inform dose selection and go/no-go decisions.   Work with preclinical and clinical CROs and company scientists to conduct and monitor clinical pharmacology studies, maintain study records and ensure study completion along program timelines.   Contribute and drive program strategy, study design, protocol preparation, study execution, data review/analysis, report preparation and regulatory document preparation.      Qualifications Ph.D. or PharmD in a relevant scientific discipline (clinical pharmacology, pharmacometrics or closely related scientific discipline).   0-2+ years' experience in pharmaceutical/biotechnology industry in regulated bioanalytical environment, preferably with multiple modalities, including small molecule, large molecule and ADC experience.   Experience in noncompartmental and PBPK analyses and pharmacometric modeling and simulation oversight including use of WINNONLIN, NONMEM, MONOLIX or similar statistical modeling software   Knowledge of R, R-shiny, SAS, MATLAB, NONMEM, MONOLIX, PBPK (gastroplus or Simcyp) or similar modeling software and substantial experience integrating quantitative clinical pharmacology with oncology drug development strategy   Familiarity with current global clinical pharmacology and pharmacometrics regulatory guidance.   Experience in development of anti-cancer agents, preferably ADCs and/or RLTs.      Knowledge and Skills Excellent written/oral communication, interpersonal and problem-solving skills.   Experience in oncology drug development with small and large molecule clinical pharmacology strategy. Experience in translational aspects of drug discovery and development is strongly preferred.   Ability to deliver integrated clinical pharmacology roadmap to registration and new product label.   Can manage multiple project related workstreams simultaneously under tight timelines collaboratively.   Experience managing clinical pharmacology related data transfers, analysis, reporting, and related timelines.   Experience interacting with global health authorities on optimal dosage design and clinical pharmacology strategy.  Effective forms of written and spoken communication is essential (eg clinical pharmacology protocols, pharmacokinetic/pharmacometric reports and regulatory submissions and performing quality control).   Knowledge of regulatory requirements governing drug development.   Resourcefulness, pragmatism, creativity, and an independent work ethic.   Washington State Pay Range$139,506—$171,900 USDE/E/O Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. E-Verify Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish). This job was verified from Greenhouse (US). Applications are completed on the original source. [Apply on the original listing ↗](https://jobradar.live/ilan/84415738-8dec-434a-9b48-23503423a572/git) ## Stop searching one by one for roles like this. Upload your resume or enter your target roles to see your first 3 matches for free. [Find jobs for me →](https://jobradar.live/uye/kayit) Your resume is never shared with employers; it is processed only for matching. Something wrong with this job? ## Similar jobs [Immunome, Inc. 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