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Bothell, Washington, United States
Posted · 20.09.2026
Greenhouse (US)

# Senior In-House Clinical Research Associate

Immunome, Inc.

Company Overview Immunome is a clinical-stage targeted oncology company committed to developing first-in-class and best-in-class targeted cancer therapies. We are advancing an innovative portfolio of therapeutics, supported by a leadership team with deep experience in the design, development, and commercialization of cutting-edge therapies, including antibody-drug conjugates. Our pipeline includes varegacestat, an investigational gamma secretase inhibitor for which an NDA has been accepted by the U.S. FDA; IM-1021, a clinical-stage ROR1 ADC; IM-1617, a clinical-stage solid tumor ADC; and IM-3050, a clinical-stage FAP-targeted radioligand therapy. We are also advancing a broad portfolio of early-stage ADCs pursuing undisclosed solid tumor targets. Position Overview The Senior&nbsp;In-house Clinical Research Associate (Sr. IHCRA) provides hands-on support for the day-to-day execution of clinical trial activities as assigned by Clinical Project Delivery (CPD) and/or Clinical Site and Trial Operations (CSTO).&nbsp;&nbsp;They operate in compliance with protocols, ICH-GCP, and applicable regulation, and Standard Operating Procedures (SOPs).&nbsp;&nbsp; This role supports functional activities across assigned trials, sites, and vendors throughout the trial lifecycle, under the guidance and oversight of CPD and CSTO to help ensure&nbsp;timely, compliant trial execution.&nbsp;&nbsp;&nbsp;&nbsp; The person in this position may&nbsp;participate&nbsp;in cross-trial process improvement initiatives and may also provide guidance to new or more junior team members.&nbsp;&nbsp; Responsibilities Project Delivery and Trial Execution Support&nbsp;&nbsp; Assist&nbsp;with completion of assigned project delivery and clinical trial operational tasks in compliance with ICH-GCP, applicable SOPs, and protocols.&nbsp;&nbsp; Help implement various study tracking tools and contribute to the development of study-level documents.&nbsp;&nbsp; Maintain study timelines as assigned.&nbsp;&nbsp; Assist&nbsp;with data review, protocol deviation review, and the query process as assigned&nbsp;&nbsp; Contribute to the development,&nbsp;maintenance&nbsp;and quality control of trial documentation, including study manuals, plans, protocols, instructions, trackers, worksheets, and presentations.&nbsp;&nbsp; Help ensure completeness, maintenance, and quality of the Trial Master File.&nbsp;&nbsp; &nbsp;&nbsp; Site Management and Monitoring Support&nbsp;&nbsp; Support site management and monitoring activities as assigned, including tasks related to site selection and activation, investigational product (IP) and clinical supplies management, site monitoring visit preparation, site-level Informed Consent review, and site contracts management.&nbsp;&nbsp; Help develop, distribute, review, track, and file essential documents and study binder documents, troubleshooting related issues to ensure on time delivery at all stages.&nbsp;&nbsp; &nbsp;Maintain site- and participant-level tracking.&nbsp;&nbsp; Support data cleaning activities as assigned&nbsp;&nbsp; &nbsp;&nbsp; Vendor Management Support&nbsp;&nbsp; Assist&nbsp;with day-to-vendor management activities including tracking and workflow management of vendor contracts.&nbsp;&nbsp; Support change order and change notification tracking, as assigned.&nbsp;&nbsp; May serve as day-to-day vendor contact for assigned activities.&nbsp;&nbsp; Participate in vendor teleconferences, record meeting minutes, track action&nbsp;items&nbsp;and decisions.&nbsp;&nbsp; Assist&nbsp;with invoice review and budget tracking.&nbsp;&nbsp; &nbsp;&nbsp; Cross-Functional Collaboration&nbsp;&nbsp; Collaborate with the clinical study team members as assigned to support consistency and efficiency of trial execution.&nbsp;&nbsp; Develop and&nbsp;maintain&nbsp;positive, effective, and collaborative working relationships with team members and vendors.&nbsp;&nbsp; Help onboard and guide new or junior team members.&nbsp;&nbsp; &nbsp;&nbsp; Qualifications Bachelor’s degree with 3 years of clinical project or trial management experience in the biotechnology or pharmaceutical industry, or an equivalent combination of education and experience.&nbsp;&nbsp; Demonstrated experience with site management and vendor management activities, including CROs and central labs.&nbsp;&nbsp;&nbsp; Demonstrated experience with trial documentation and Trial Master File management.&nbsp; &nbsp;&nbsp; Knowledge and Skills Working knowledge of clinical trial processes, and ICH-GCP.&nbsp;&nbsp; Strong organizational skills with the ability to manage multiple competing tasks.&nbsp;&nbsp; Ability to effectively work cross-functionally and build relationships with stakeholders without direct authority.&nbsp;&nbsp; Strong communication&nbsp;and interpersonal skills.&nbsp;&nbsp; Detail-oriented with an analytical approach to problem-solving.&nbsp;&nbsp; Able to prioritize and manage multiple tasks and projects in a fast-paced, dynamic environment.&nbsp;&nbsp; Highly professional, adaptable, and accountable.&nbsp;&nbsp; Washington State Pay Range$127,890&mdash;$155,682 USDE/E/O Immunome, Inc. is an equal opportunity employer. We celebrate diversity and are committed to creating an inclusive environment for all employees. E-Verify Immunome, Inc. is a participant in E-Verify. Please review the following notices: E-Verify Participation Poster | Right to Work Poster (English) | Right to Work Poster (Spanish).

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