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Active
Hybrid
San Francisco Bay Area Hybrid, California, United States
Posted · 18.09.2026
Ashby (US)

# Senior Machine Learning Engineer (Clinical Team)

Midjourney

WHAT YOU’LL DO
1. Own the tissue-class segmentation and labeling models for the ultrasound CT clinical analysis layer, and the pipelines that make them trainable and verifiable.
2. Retune across 2D per-slice, 3D volumetric, and 2D×3D fusion as reconstructed image inputs are continuously updated, and clinical indications for use expand.
3. Define training/evaluation pipelines, datasets, and metrics from the ground up or from open source; map model behavior to user needs and design requirements.
4. Work with data labeling contractors, expert clinicians, and our internal cloud/data teams on labeling specs, QC, and dataset versioning.
5. Help productionize models into a versioned, HIPAA-bound analysis service: reproducible/low-latency inference, per-prediction confidence, drift monitoring, and safe fallbacks.
WHAT WE’RE LOOKING FOR
• Strong applied ML experience with a track record of developing new models — architecting, training, and evaluating from scratch as well as benchmarking against existing models.
• Experience with image segmentation (semantic/instance, 2D and ideally 3D/volumetric) and the modeling and training-data choices that make it robust across diverse patient anatomy.
• Comfortable moving fluidly between open-ended research iteration and producing quantifiable, testable models.
• Fluent in modern deep-learning tooling (e.g., PyTorch) and current development practices.
• Comfortable working under design controls, where model changes carry documentation and verification weight.
USEFUL EXPERIENCE
• Image segmentation and label generation with modern architectures (U-Net / nnU-Net, 3D U-Net, transformer-based and promptable segmentation like SAM), including the geometry that ties voxel- and mesh-level predictions back to a coordinate frame.
• Learning under limited or noisy supervision: self-supervised / semi-supervised methods (masked autoencoders, contrastive pretraining like DINO/SimCLR), active learning, weak labels, and simulation-driven pretraining.
• Hands-on experience with data curation for ML: building datasets from messy, real-world sources, helping to define ground truth, and managing labeling or simulation pipelines (MONAI, ITK / SimpleITK, 3D Slicer).
• Experience with segmentation models for ultrasound imaging, whether on synthetic or real images
• ML for imaging or inverse problems in physics-based domains (CT, MRI, ultrasound, or adjacent), and comfort working alongside reconstruction/signal-processing teams.
• Deploying models in versioned, auditable, high-stakes settings.
• A background in anatomy, medical imaging, or body composition and prior work with existing segmentation models is a plus.

This job was verified from Ashby (US). Applications are completed on the original source.

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